Catching the mode of action
نویسندگان
چکیده
منابع مشابه
Catching Evolution in Action
To study evolution, biologists have traditionally investigated what has happened in the past, sometimes many millions of years ago. To learn about dinosaurs, a paleontologist looks at dinosaur fossils. To study human evolution, an anthropologist looks at human fossils and, increasingly, examines the “family tree” of mutations that have accumulated in human DNA over millions of years. For the bi...
متن کاملCatching evolution in action
A hundred years ago Charles Darwin’s theory of evolution by natural selection was taught as the foundation of biology in public schools throughout the United States. Then something happened. In the 1920s, conservative religious groups began to argue against the teaching of evolution in our nation's schools. Darwinism, they said, contradicted the revealed word of God in the Bible and thus was a ...
متن کاملCatching synaptic vesicles in action
The synaptic vesicle (SV) cycle was initially discovered at the neuromuscular junction using electron microscopy (EM) analysis.(1) With the introduction of fluorescent probes that are able to monitor real-time cellular events in live cells, EM analysis was pushed to the side lines because it could not provide meaningful kinetic analyses of the various steps in the synaptic vesicle cycle.
متن کاملCatching the sources of organic LED degradation in action
Though great improvements have been made in recent years, organic light emitting diodes (OLEDs) still have limited lifetimes. In general, the degradation of OLEDs manifests itself as a decrease in device luminance with time. Three distinct modes of deterioration have been recognized: dark spot generation, catastrophic failure, and intrinsic degradation.1 In the first mode, nonemissive regions a...
متن کاملMode of Action
Being impermeable to folic acid, many bacteria must rely on their ability to synthesise folate from PABA, Pteridine, and glutamate in contrast the mammalian in cells cannot synthesise folic acid and must obtain preformed folate as a vitamin in their diet. The sulphonamides are structurally similar to PABA, the sulphonamides competitively inhibit dihydropteroate synthetase, the enzyme that catal...
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ژورنال
عنوان ژورنال: Nature Reviews Microbiology
سال: 2020
ISSN: 1740-1526,1740-1534
DOI: 10.1038/s41579-020-0411-2